{"product_id":"dysport-500u-abobotulinumtoxina-fda-ema-approved-ipsen","title":"Dysport 500U — AbobotulinumtoxinA | FDA \u0026 EMA Approved | Ipsen","description":"\u003cp\u003eDysport (AbobotulinumtoxinA) — The European-Origin Botulinum Toxin \u003cbr\u003eStandard for Aesthetic \u0026amp; Therapeutic Practice\u003c\/p\u003e\n\u003cp\u003eDeveloped by Ipsen Biopharmaceuticals, one of the world's leading \u003cbr\u003especialty pharmaceutical companies, Dysport (abobotulinumtoxinA) \u003cbr\u003eis a globally approved botulinum toxin type A with decades of \u003cbr\u003eclinical evidence across both aesthetic and therapeutic indications. \u003cbr\u003eFDA-approved since 2009, EMA-approved, and trusted by practitioners \u003cbr\u003eacross more than 80 countries worldwide.\u003c\/p\u003e\n\u003cp\u003eDysport's abobotulinumtoxinA formulation is distinct from other \u003cbr\u003ebotulinum toxin preparations — its unique diffusion profile and \u003cbr\u003eunit system are specific to Ipsen's proprietary assay method and \u003cbr\u003eare not interchangeable with any other botulinum toxin product.\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eProduct Specifications\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003eProduct Name      : Dysport (AbobotulinumtoxinA)\u003cbr\u003eActive Ingredient : AbobotulinumtoxinA (Clostridium botulinum\u003cbr\u003e                    Toxin Type A, Hall Strain)\u003cbr\u003eAvailable Strengths: 300 Units \/ 500 Units per vial\u003cbr\u003eComposition       : AbobotulinumtoxinA + Human Serum Albumin\u003cbr\u003e                    (125 mcg) + Lactose (2.5 mg)\u003cbr\u003eAppearance        : Sterile lyophilized white powder\u003cbr\u003ePreservative      : Preservative-free\u003cbr\u003eStorage (Unrecon.): 2°C – 8°C, protect from light\u003cbr\u003eStorage (Recon.)  : 2°C – 8°C, use within 24 hours\u003cbr\u003eCountry of Origin : Europe (Ipsen Biopharmaceuticals)\u003cbr\u003eManufacturer      : Ipsen Biopharmaceuticals\u003cbr\u003eCertifications    : FDA (USA) · EMA (Europe) · GMP\u003c\/p\u003e\n\u003cp\u003e⚠ Unit Note: Dysport units are specific to Ipsen's assay method.\u003cbr\u003e  They are NOT interchangeable with units of any other botulinum\u003cbr\u003e  toxin product including Botox, Nabota, or Xeomin.\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eWhat is AbobotulinumtoxinA?\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003eDysport contains abobotulinumtoxinA — a specific serotype of \u003cbr\u003epurified botulinum toxin type A complex derived from the Hall \u003cbr\u003eStrain of Clostridium botulinum. Its mechanism of action involves:\u003c\/p\u003e\n\u003cp\u003e1. Heavy chain binding to presynaptic nerve terminal receptors\u003cbr\u003e2. Receptor-mediated endocytosis into the nerve ending\u003cbr\u003e3. Light chain cleavage of SNAP-25 protein\u003cbr\u003e4. Blockade of acetylcholine release at the neuromuscular junction\u003cbr\u003e5. Reversible local muscle relaxation\u003c\/p\u003e\n\u003cp\u003eCompared to other botulinum toxin preparations, Dysport is \u003cbr\u003eknown for its relatively wider diffusion radius — making it \u003cbr\u003eparticularly suited for larger treatment areas such as the \u003cbr\u003eforehead, platysmal bands, and spasticity applications.\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eClinical Indications\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003eAesthetic (FDA-Approved)\u003cbr\u003e✔ Glabellar lines (frown lines) — 50 Units standard dose\u003cbr\u003e✔ Forehead lines\u003cbr\u003e✔ Crow's feet (lateral canthal lines)\u003cbr\u003e✔ Platysmal bands (neck rejuvenation)\u003cbr\u003e✔ Brow lifting\u003cbr\u003e✔ Masseteric reduction (jawline slimming)\u003c\/p\u003e\n\u003cp\u003eTherapeutic (FDA-Approved)\u003cbr\u003e✔ Cervical dystonia — 500 Units initial dose\u003cbr\u003e✔ Adult upper limb spasticity — 500–1,000 Units\u003cbr\u003e✔ Adult lower limb spasticity — 1,000–1,500 Units\u003cbr\u003e✔ Pediatric lower limb spasticity (≥2 years)\u003cbr\u003e✔ Axillary hyperhidrosis\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eOnset \u0026amp; Duration\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003e- Initial effect: 2–4 days post-injection\u003cbr\u003e- Peak effect: 2–4 weeks\u003cbr\u003e- Duration: 3–5 months (aesthetic indications)\u003cbr\u003e- Retreatment interval: minimum every 3 months\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eReconstitution Guide\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003e300 Unit Vial\u003cbr\u003e- 2.5 mL saline → 120 Units per 1.0 mL\u003cbr\u003e- 3.0 mL saline → 100 Units per 1.0 mL\u003c\/p\u003e\n\u003cp\u003e500 Unit Vial\u003cbr\u003e- 1.0 mL saline → 500 Units per 1.0 mL\u003cbr\u003e- 2.5 mL saline → 200 Units per 1.0 mL\u003c\/p\u003e\n\u003cp\u003eReconstitute with preservative-free 0.9% Sodium Chloride.\u003cbr\u003eSwirl gently — do not shake. Use within 24 hours of reconstitution.\u003cbr\u003eSingle patient, single session use only.\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eDysport vs Nabota — Quick Reference\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003e                  Dysport             Nabota\u003cbr\u003eType              AbobotulinumtoxinA  OnabotulinumtoxinA\u003cbr\u003eOrigin            Europe (Ipsen)      Korea (Daewoong)\u003cbr\u003eUnits             Ipsen-specific      Daewoong-specific\u003cbr\u003eDiffusion         Wider spread        More localized\u003cbr\u003eBest For          Larger areas,       Precise focal\u003cbr\u003e                  spasticity          treatment\u003cbr\u003eFDA Approval      2009                2019 (as Jeuveau)\u003cbr\u003eStrengths         300U \/ 500U         100U \/ 200U\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eSafety \u0026amp; Compliance\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003e✔ FDA-approved (2009) · EMA-approved · GMP-manufactured\u003cbr\u003e✔ Preservative-free — single-dose vials\u003cbr\u003e✔ \u0026gt;80 countries global distribution\u003cbr\u003e✔ Decades of clinical safety data across aesthetic \u0026amp; therapeutic use\u003cbr\u003e✔ Cold-chain compliant shipping (2°C – 8°C maintained)\u003c\/p\u003e\n\u003cp\u003eContraindications: Known hypersensitivity to any botulinum toxin \u003cbr\u003eproduct or cow's milk protein. Infection at proposed injection site.\u003cbr\u003eNot for use during pregnancy or lactation.\u003c\/p\u003e\n\u003cp\u003eFor use by licensed medical and aesthetic professionals only.\u003cbr\u003eDysport units are not interchangeable with any other botulinum \u003cbr\u003etoxin product. Refer to full prescribing information before use.\u003c\/p\u003e","brand":"Holypath","offers":[{"title":"Default Title","offer_id":53465829572792,"sku":null,"price":0.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0938\/6069\/2152\/files\/Dysport.png?v=1778773661","url":"https:\/\/holypathglobal.com\/products\/dysport-500u-abobotulinumtoxina-fda-ema-approved-ipsen","provider":"Holypath","version":"1.0","type":"link"}