Nabota 100U — Botulinum Toxin Type A | FDA-Approved | Daewoong Korea

Nabota 100U — Korea's Most Globally Certified Botulinum Toxin Type A

Developed by Daewoong Pharmaceutical, one of South Korea's leading 
biopharmaceutical companies with over 30 years of biotechnology expertise. 
Nabota is the first Asian botulinum toxin to receive simultaneous approval 
from the U.S. FDA, European EMA, and Health Canada — setting the global 
benchmark for Korean neurotoxin quality.

In the United States, Nabota is marketed as Jeuveau® by Evolus Inc., 
the only botulinum toxin in the U.S. approved exclusively for aesthetic 
indications.

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Product Specifications
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Product Name      : Nabota 100U
Active Ingredient : Clostridium Botulinum Toxin Type A
Concentration     : 100 Units per vial
Composition       : Botulinum Toxin Type A, Human Serum Albumin 
                    (0.5 mg), Sodium Chloride (0.9 mg)
Appearance        : White to yellowish lyophilized powder
Preservative      : Preservative-free (hypoallergenic)
Purity            : >98.7% (Hi-Pure Technology™)
Storage           : 2°C – 8°C (Do not freeze)
Shelf Life        : 36 months
Country of Origin : South Korea
Manufacturer      : Daewoong Pharmaceutical Co., Ltd.
Certifications    : FDA (USA) · EMA (Europe) · MFDS (Korea) · CE · GMP

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Hi-Pure Technology™
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Nabota is manufactured using Daewoong's patented Hi-Pure Technology — 
a proprietary purification process that achieves >98.7% purity of the 
900 kDa botulinum toxin complex by removing accessory proteins and 
impurities. This results in:

✔ Reduced risk of antibody resistance
✔ Consistent, predictable clinical outcomes
✔ Lower adverse reaction profile
✔ Superior batch-to-batch stability

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Clinical Indications
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Aesthetic
✔ Glabellar lines (frown lines)
✔ Forehead lines
✔ Crow's feet (lateral canthal lines)
✔ Jawline slimming (masseter reduction)
✔ Brow lifting
✔ Neck bands (platysmal bands)
✔ Perioral wrinkles and lip lines
✔ Skin Botox (micro-injection for pore & texture)

Therapeutic
✔ Hyperhidrosis (axillary, palmar, plantar)
✔ Blepharospasm
✔ Spasticity associated with stroke

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Onset & Duration
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- Initial effect: 2–3 days post-injection
- Peak effect: 1–2 weeks
- Duration: 3–6 months (indication-dependent)
- Retreatment interval: 3–6 months

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Reconstitution Guide
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Dilute with 2.5–4 mL of sterile, preservative-free 0.9% saline.
Inject using a 30–33G needle. Use within 24 hours of reconstitution.
Refer to full prescribing information for site-specific dosing.

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Safety & Compliance
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✔ Preservative-free — hypoallergenic formulation
✔ FDA-approved · EMA-approved · MFDS-certified
✔ GMP-manufactured under international pharmaceutical standards
✔ Cold-chain compliant shipping (2°C – 8°C maintained)

For use by licensed medical and aesthetic professionals only.