Elravie Re2O Skin Booster | hADM ECM — Collagen & Elastin Direct Replenishment

Elravie Re2O (Ritwho) — The World's First ECM Skin Booster

A paradigm shift in aesthetic regenerative medicine. Elravie Re2O is the 
first injectable skin booster in the world to utilize hADM (human Acellular 
Dermal Matrix) — delivering real human dermal ECM components directly into 
the skin, not merely stimulating collagen production.

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What Makes Re2O Different
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Previous generations of skin boosters operate through indirect mechanisms:

  1st Gen — Hyaluronic Acid: volume and hydration only
  2nd Gen — PN/PDRN (Rejuran): collagen synthesis stimulation
  3rd Gen — PDLLA (Juvelook): foreign-body reaction-induced collagen
  4th Gen — ECM Booster (Re2O): direct ECM replenishment ← NEW

Elravie Re2O goes further. Rather than triggering a collagen response, 
it directly supplements the Extracellular Matrix (ECM) — the structural 
framework of the dermis — using processed human acellular dermal tissue 
containing collagen, elastin, and hyaluronic acid in their native 
three-dimensional architecture.

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Core Technology
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hADM (human Acellular Dermal Matrix)
Real human dermal tissue, processed to remove cellular and 
immunogenic components while preserving the full ECM structure — 
collagen, elastin, fibronectin, laminin, and native HA.

AlloClean Technology™ (Patented — L&C Bio)
Proprietary processing method that removes immune rejection factors 
without disrupting the tissue's native 3D matrix architecture. 
Unlike xenograft (porcine/bovine) collagen, hADM-derived ECM 
eliminates cross-species immune response risk.

Manufactured by Humedix × L&C Bio
The combined expertise of Humedix — Korea's leading HA filler 
manufacturer — and L&C Bio, a certified AATB (American Association 
of Tissue Banks) member, one of only two in Korea.

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Clinical Indications
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✔ Pore refinement and skin texture improvement  
✔ Fine line and wrinkle reduction  
✔ Skin density and dermal thickness restoration  
✔ Brightening — pigmentation and uneven skin tone  
✔ Post-procedure skin recovery and barrier reinforcement  
✔ Overall dermal ECM regeneration for anti-aging protocols

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Treatment Protocol
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- Initial effects visible from Day 3 post-treatment  
- Full texture and pore improvement: 1–2 weeks  
- Recommended cycle: 3–4 week intervals, minimum 3 sessions  
- Compatible combination: Re2O + Re2O Fine (periocular/perioral areas)  
- Synergistic pairing: Re2O + Skin Botox for enhanced pore reduction

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Safety Profile
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✔ Human-origin (allograft) ECM — no xenograft immune risk  
✔ AlloClean Technology™ removes all cellular immunogenic factors  
✔ Biocompatibility certified — AATB standards  
✔ Suitable for sensitive skin types  
✔ Minimal downtime — light cleansing from 3–4 hours post-procedure

For use by licensed medical and aesthetic professionals only.
Manufactured in South Korea under GMP standards.