{"product_id":"rejuran-hb","title":"Rejuran HB — PN + HA Skin Booster | Hydration \u0026 Regeneration | Lidocaine | 1x1ml","description":"\u003cp\u003eRejuran HB — PN × HA Dual-Action Skin Booster for Regeneration \u0026amp; Hydration\u003c\/p\u003e\n\u003cp\u003eThe only Rejuran formulation that combines two regenerative mechanisms \u003cbr\u003ein a single vial: salmon-derived Polynucleotide (PN) for cellular \u003cbr\u003eregeneration, and Hyaluronic Acid (HA) for immediate deep hydration — \u003cbr\u003ewith 0.3% Lidocaine for a significantly more comfortable injection \u003cbr\u003eexperience.\u003c\/p\u003e\n\u003cp\u003eWhere Rejuran Healer focuses on long-term structural repair, Rejuran HB \u003cbr\u003edelivers visible results from day one — making it the ideal entry point \u003cbr\u003efor first-time patients, and the most versatile option for dry, dehydrated, \u003cbr\u003eor UV-damaged skin that requires both repair and immediate moisture.\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eProduct Specifications\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003eProduct Name      : Rejuran HB (Hydration Booster)\u003cbr\u003eActive Ingredients: Polynucleotide (PN) 1% + Hyaluronic Acid (HA) 1%\u003cbr\u003eAdded Component   : Lidocaine 0.3% (pain reduction)\u003cbr\u003eForm              : Injectable solution\u003cbr\u003ePack Size         : 1 x 1ml pre-filled syringe\u003cbr\u003eInjection Depth   : Superficial to mid-dermis\u003cbr\u003eStorage           : 2°C – 25°C, away from direct light\u003cbr\u003eShelf Life        : 24 months\u003cbr\u003eCountry of Origin : South Korea\u003cbr\u003eManufacturer      : PharmaResearch Co., Ltd.\u003cbr\u003eCertifications    : KGMP · ISO 13485 · CE · KFDA\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eThe PN + HA Synergy — Why the Combination Matters\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003ePN and HA do not simply coexist in this formula — they amplify \u003cbr\u003eeach other's effects through complementary mechanisms:\u003c\/p\u003e\n\u003cp\u003ePN (Polynucleotide) — Regeneration Layer\u003cbr\u003eActivates fibroblast proliferation, stimulates Type I\/III collagen \u003cbr\u003eand elastin synthesis, and repairs the extracellular matrix (ECM) \u003cbr\u003eat the cellular level. Long-term structural skin rebuilding.\u003c\/p\u003e\n\u003cp\u003eHA (Hyaluronic Acid) — Hydration Layer\u003cbr\u003eBinds up to 1,000x its weight in water within the dermis, \u003cbr\u003edelivering immediate volumetric hydration and improving the \u003cbr\u003eskin's moisture-retention capacity from the first session.\u003c\/p\u003e\n\u003cp\u003eCombined Synergistic Effects\u003cbr\u003e✔ ECM hydration — HA maintains the aqueous environment \u003cbr\u003e  in which PN-driven fibroblasts function optimally\u003cbr\u003e✔ Accelerated fibroblast proliferation — HA scaffolding \u003cbr\u003e  enhances PN's cell-signaling efficiency by up to 20%\u003cbr\u003e✔ Collagen synthesis — dual stimulation from both PN \u003cbr\u003e  (biological) and HA (mechanical) pathways\u003cbr\u003e✔ Skin barrier reinforcement — combined ECM support \u003cbr\u003e  strengthens the dermal architecture comprehensively\u003c\/p\u003e\n\u003cp\u003eLidocaine 0.3% — Comfort Protocol\u003cbr\u003eSignificantly reduces injection discomfort, making Rejuran HB \u003cbr\u003ethe most patient-friendly option in the Rejuran line — ideal \u003cbr\u003efor pain-sensitive patients and high-frequency treatment areas.\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eClinical Indications\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003eHydration \u0026amp; Glow\u003cbr\u003e✔ Severely dry and dehydrated skin\u003cbr\u003e✔ Dull, fatigued complexion lacking radiance\u003cbr\u003e✔ Moisture-barrier-compromised skin\u003c\/p\u003e\n\u003cp\u003eRegeneration \u0026amp; Anti-Aging\u003cbr\u003e✔ Fine lines and superficial wrinkles\u003cbr\u003e✔ Early-to-moderate signs of skin aging\u003cbr\u003e✔ Loss of skin elasticity and firmness\u003c\/p\u003e\n\u003cp\u003eDamage Repair\u003cbr\u003e✔ UV-damaged and photoaged skin\u003cbr\u003e✔ Skin damaged by excessive cosmetic treatments\u003cbr\u003e✔ Post-laser and post-peel skin recovery\u003c\/p\u003e\n\u003cp\u003eTexture \u0026amp; Tone\u003cbr\u003e✔ Uneven skin tone and roughness\u003cbr\u003e✔ Enlarged pores\u003cbr\u003e✔ Superficial acne scarring\u003c\/p\u003e\n\u003cp\u003eTreatment Areas\u003cbr\u003e✔ Full face and neck\u003cbr\u003e✔ Décolletage\u003cbr\u003e✔ Elbows, knees, and back of hands\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eTreatment Protocol\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003e- Initial course: 3–4 sessions at 3–4 week intervals\u003cbr\u003e- Visible hydration: from Day 1 post-treatment\u003cbr\u003e- Structural improvement: progressive over treatment course\u003cbr\u003e- Duration of effect: 6–12 months\u003cbr\u003e- Maintenance: every 6 months\u003cbr\u003e- Combination: pair with Rejuran Healer for comprehensive\u003cbr\u003e  full-face regeneration + hydration protocol on the same day\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eRejuran HB vs Rejuran Healer — Quick Reference\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003e                  Rejuran Healer    Rejuran HB\u003cbr\u003eActive            PN only           PN + HA + Lidocaine\u003cbr\u003eVolume            2 x 2ml           1 x 1ml\u003cbr\u003eHydration         Long-term         Immediate + Long-term\u003cbr\u003ePain Level        Moderate          Reduced (Lidocaine)\u003cbr\u003eBest For          Regeneration      Regeneration + Hydration\u003cbr\u003ePatient Profile   All skin types    Dry, dehydrated,\u003cbr\u003e                                    first-time patients\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eSafety \u0026amp; Compliance\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003e✔ 2-fold improvement in elasticity vs HA-only boosters (clinical data)\u003cbr\u003e✔ No immune or allergic responses in clinical studies\u003cbr\u003e✔ Lidocaine reduces procedural discomfort significantly\u003cbr\u003e✔ KGMP \u0026amp; ISO 13485 certified manufacturing\u003cbr\u003e✔ CE marked — European medical device compliance\u003cbr\u003e✔ Minimal downtime — redness resolves within 24–48 hrs\u003c\/p\u003e\n\u003cp\u003eNote: Avoid concurrent use with cross-linked HA fillers.\u003cbr\u003eDo not administer within 12 months of cross-linked HA injection \u003cbr\u003edue to granuloma risk. Not for pregnant or lactating patients.\u003c\/p\u003e\n\u003cp\u003eFor use by licensed medical and aesthetic professionals only.\u003cbr\u003eManufactured in South Korea under GMP standards.\u003c\/p\u003e","brand":"PharmaResearch","offers":[{"title":"Default Title","offer_id":53465827836088,"sku":null,"price":0.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0938\/6069\/2152\/files\/RejuranHB.png?v=1778773516","url":"https:\/\/holypathglobal.com\/products\/rejuran-hb","provider":"Holypath","version":"1.0","type":"link"}