{"product_id":"rejuran-healer","title":"Rejuran Healer — PN Skin Booster | Salmon DNA | 2 x 2ml | PharmaResearch Korea","description":"\u003cp\u003eRejuran Healer — Korea's Pioneering PN Skin Booster for Cellular Regeneration\u003c\/p\u003e\n\u003cp\u003eThe original and most trusted polynucleotide (PN) injectable in Korean \u003cbr\u003eaesthetic medicine. Developed by PharmaResearch Co., Ltd. using patented \u003cbr\u003eDOT™ (DNA Optimizing Technology), Rejuran Healer delivers highly purified \u003cbr\u003esalmon-derived PN directly into the dermis — stimulating the skin's own \u003cbr\u003eregenerative processes at the cellular level.\u003c\/p\u003e\n\u003cp\u003eUnlike hyaluronic acid boosters that hydrate from the outside in, Rejuran \u003cbr\u003eHealer rebuilds skin architecture from within — activating fibroblasts, \u003cbr\u003erestoring collagen and elastin networks, and repairing damaged ECM.\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eProduct Specifications\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003eProduct Name      : Rejuran Healer (Skin Healer)\u003cbr\u003eActive Ingredient : Polynucleotide (PN) — Salmon DNA-derived\u003cbr\u003eForm              : Injectable solution\u003cbr\u003ePack Size         : 2 x 2ml pre-filled syringes\u003cbr\u003eInjection Depth   : Superficial to mid-dermis\u003cbr\u003eNeedle Size       : 33G x 4mm (recommended)\u003cbr\u003eStorage           : 2°C – 25°C, away from direct light\u003cbr\u003eShelf Life        : 24 months\u003cbr\u003eCountry of Origin : South Korea\u003cbr\u003eManufacturer      : PharmaResearch Co., Ltd.\u003cbr\u003eCertifications    : KGMP · ISO 13485 · CE · KFDA\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eKey Technology — DOT™ (DNA Optimizing Technology)\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003eRejuran's proprietary DOT™ technology extracts and purifies PN from \u003cbr\u003eKorean Chum Salmon (Oncorhynchus keta) — the species with the closest \u003cbr\u003eDNA base composition to the human genome, ensuring maximum biocompatibility.\u003c\/p\u003e\n\u003cp\u003ePN vs PDRN: What's the Difference?\u003cbr\u003ePDRN (Polydeoxyribonucleotide) is a broader class of DNA fragments.\u003cbr\u003ePN (Polynucleotide) is a more purified, concentrated form with longer \u003cbr\u003echain structures — enabling extended presence in dermal tissue, stronger \u003cbr\u003eregenerative activity, and more consistent clinical outcomes.\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eMechanism of Action\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003e✔ Fibroblast Activation — stimulates proliferation of skin's collagen-\u003cbr\u003e  producing cells by up to 20%, driving long-term structural repair\u003cbr\u003e✔ Collagen \u0026amp; Elastin Synthesis — promotes Type I\/III collagen growth \u003cbr\u003e  and elastin network restoration for improved skin density and firmness\u003cbr\u003e✔ Anti-Inflammatory Action — scavenges free radicals and blocks \u003cbr\u003e  inflammatory cytokines, reducing redness and skin sensitivity\u003cbr\u003e✔ ECM Restoration — rebuilds the extracellular matrix framework \u003cbr\u003e  that deteriorates with age and UV exposure\u003cbr\u003e✔ Growth Factor Stimulation — enhances microcirculation and accelerates \u003cbr\u003e  natural wound healing processes in the dermis\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eClinical Indications\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003eSkin Regeneration \u0026amp; Anti-Aging\u003cbr\u003e✔ Fine lines and wrinkles (periorbital, perioral, forehead, neck)\u003cbr\u003e✔ Skin laxity and loss of elasticity\u003cbr\u003e✔ Skin thinning and reduced dermal density\u003c\/p\u003e\n\u003cp\u003eTexture \u0026amp; Tone\u003cbr\u003e✔ Enlarged pores\u003cbr\u003e✔ Uneven skin tone and dullness\u003cbr\u003e✔ Sebum-moisture imbalance\u003c\/p\u003e\n\u003cp\u003eScar \u0026amp; Damage Repair\u003cbr\u003e✔ Atrophic acne scars\u003cbr\u003e✔ Post-laser and post-procedure skin recovery\u003cbr\u003e✔ Sun damage and photoaging repair\u003cbr\u003e✔ Stretch marks\u003c\/p\u003e\n\u003cp\u003eRejuran Line Variants\u003cbr\u003e✔ Rejuran Healer   — Full face, all skin types (standard PN)\u003cbr\u003e✔ Rejuran I        — Periocular area, crow's feet, under-eye (fine PN)\u003cbr\u003e✔ Rejuran S        — Depressed and sunken acne scars (viscous PN)\u003cbr\u003e✔ Rejuran HB       — PN + HA combination for enhanced hydration\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eTreatment Protocol\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003e- Initial course: 3–4 sessions at 2–4 week intervals\u003cbr\u003e- Visible improvement: from 2–3 days post-treatment\u003cbr\u003e- Optimal results: after completion of full session course\u003cbr\u003e- Maintenance: once every 6–9 months\u003cbr\u003e- Injection volume: approximately 2ml per full face treatment\u003cbr\u003e- Compatible with: mesotherapy, microneedling, skin botox protocols\u003c\/p\u003e\n\u003cp\u003eNote: Avoid concurrent use with cross-linked HA fillers. \u003cbr\u003eDo not use in patients who have received cross-linked HA injections \u003cbr\u003ewithin the prior 12 months due to granuloma risk.\u003c\/p\u003e\n\u003cp\u003e──────────────────────────────────────\u003cbr\u003eSafety \u0026amp; Compliance\u003cbr\u003e──────────────────────────────────────\u003c\/p\u003e\n\u003cp\u003e✔ Highly biocompatible — salmon DNA closely mirrors human genome structure\u003cbr\u003e✔ No immune or allergic response reported in clinical studies\u003cbr\u003e✔ KGMP \u0026amp; ISO 13485 certified manufacturing\u003cbr\u003e✔ CE marked — compliant with European medical device regulations\u003cbr\u003e✔ Minimal downtime — 2–5 day recovery; redness resolves within 24–48 hrs\u003c\/p\u003e\n\u003cp\u003eFor use by licensed medical and aesthetic professionals only.\u003cbr\u003eManufactured in South Korea under GMP standards.\u003c\/p\u003e","brand":"PharmaResearch","offers":[{"title":"Default Title","offer_id":53465822068920,"sku":null,"price":0.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0938\/6069\/2152\/files\/rejuranHealer.png?v=1778773220","url":"https:\/\/holypathglobal.com\/products\/rejuran-healer","provider":"Holypath","version":"1.0","type":"link"}